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Handbook of Nucleoside Synthesis
Helmut Vorbrüggen; Carmen Ruh-Pohlenz
A comprehensive survey of established and experimental methods in nucleoside synthesis This volume presents a comprehensive review of nucleoside synthesis with a uniquely broad perspective. It describes the three principal types of nucleoside-forming reactions–the fusion reaction, the metal salt procedure, and the Hilbert-Johnson reaction–as well as a number of other methods, and presents a broad overview of alternative chemical methods for synthesis.

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This comprehensive discussion includes a survey of experimental protocols for nucleoside synthesis, instructions on preparing components for the reaction, and a sampling of precise experimental procedures for the Vorbrüggen glycosylation reaction. Protocols for a variety of Lewis acid catalysts and carbohydrate precursors are also provided.