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Methods and Principles in Medicinal Chemistry: Microwaves in Organic and Medicinal Chemistry, Volume 25 |
| Methods and Principles in Medicinal Chemistry |
| C. Oliver Kappe (University of Graz, Austria); Alexander Stadler (University of Graz, Austria); Series Editor: Raimund Mannhold (University of Duesseldorf, Germany); Series Editor: Hugo Kubinyi (University of Heidelberg, Germany); Series Editor: Gerd Folkers (Swiss Institute of Technology (ETH), Zürich, Switzerland) |
| The complete guide to microwave synthesis in medicinal chemistry synthesis -- while also containing a "crash-course" for newcomers. Compared to conventional heating methods, microwave irradiation causes less side-reactions and losses through decomposition and can be easily adapted to different chemical reaction conditions. Cheap and reliable, this method has been successfully used for a variety of chemical reactions, most notably in the synthesis of drugs and drug-like compounds.
In this handy reference, the authors focus on common reaction types in medicinal chemistry, including solid-phase and combinatorial methods. They consider the underlying theory, latest developments in microwave applications and include a variety of examples from recent literature, as well as less common applications that are equally relevant for organic and medicinal chemists. From the contents: *Introduction *Microwave theory *Equipment review *Microwave processing techniques *Getting started with microwave chemistry *Literature survey: general organic synthesis *Literature survey: combinatorial and high-throughput synthesis The authors are all experts on the use of microwaves for drug synthesis and have ample teaching experience from courses held under the auspices of the American Chemical Society and the IUPAC. The result is an indispensable information source for organic and medicinal chemists, as well as those in industry and the pharmaceutical industry.
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| Cloth Bound |
422 Pages
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Item #:
Price: |
3527312102
$200.00 |
John Wiley & Sons, Inc. | |
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