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Voltage-Gated Ion Channels as Drug Targets |
| Methods and Principles in Medicinal Chemistry |
| Editor: David J. Triggle (State University of New York, Buffalo, USA); Editor: Murali Gopalakrishnan (Abbott Laboratories, Abbott Park, USA); Editor: David Rampe (Aventis Pharmaceuticals, Bridgewater, USA); Editor: Wei Zheng (Merck & Co., North Wales, USA); Series Editor: Raimund Mannhold (University of Düsseldorf, Germany); Series Editor: Hugo Kubinyi (University of Heidelberg, Germany); Series Editor: Gerd Folkers (Swiss Institute of Technology (ETH), Zürich, Switzerland) |
| Edited by the most prominent person in the field and top researchers at US pharmaceutical companies, this is a unique resource for drug developers and physiologists seeking a molecular-level understanding of ion channel pharmacology. After an introduction to the topic, the authors evaluate the structure and function of ion channels, as well as related drug interaction. A section on assay technologies is followed by a section each on calcium, sodium and potassium channels. Further chapters cover genetic and acquired channelopathies, before the book closes with a look at safety issues in ion channel drug development. For medicinal and pharmaceutical chemists, biochemists, molecular biologists and those working in the pharmaceutical industry.
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| Cloth Bound |
492 Pages
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Item #:
Price: |
3527312587
$200.00 |
John Wiley & Sons, Inc. | |
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