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Directed Molecular Evolution of Proteins: or How to Improve Enzymes for Biocatalysis |
| Editor: Susanne Brakmann; Editor: Kai Johnsson |
| Natural selection created optimal catalysts. However, optimal performance of enzyme catalysis does not necessarily refer to maximum reaction rate. Rather, it may be a compromise between specificity, rate, stability, and other chemical constraints that makes enzymes capable of catalyzing reactions under mild conditions and with high substrate specificity, accompanied by high regio- and enantioselectivity. The book presented here focuses on the directed evolution of proteins, which has established itself as a powerful method for designing enzymes showing new substrate specificities. It includes a comprehensive repertoire of techniques for producing combinatorial enzyme libraries, while the functional gene expression in a suitable host helps in selecting the appropriate structure, making fast screening a necessity. This book illustrates both the theoretical background as well as the potential of this interesting method in practice - which is becoming ever more important even in classical organic synthesis!
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| Cloth Bound |
360 Pages
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Item #:
Price: |
3527304231
$140.00 |
John Wiley & Sons, Inc. | |
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Item #3527306919
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Modern Fluoroorganic Chemistry: Synthesis, Reactivity, Applications
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Cloth - $210.00
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Item #0471253162
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Topics in Stereochemistry, Volume 22,
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Cloth - $160.00
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Synthetic Applications of 1,3-Dipolar Cycloaddition Chemistry Toward Heterocycles and Natural Products
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Paperback - $127.50
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Item #047002321X
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The Chemistry of Organolithium Compounds, Volume 2,
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Cloth - $
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Item #0471235857
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Reviews in Computational Chemistry, Volume 19,
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Cloth - $210.00
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Item #3527312102
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Methods and Principles in Medicinal Chemistry: Microwaves in Organic and Medicinal Chemistry, Volume 25
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Cloth - $200.00
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