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BioNMR in Drug Research |
| Series Editor: Raimund Mannhold (Inst. f. Lasermedizin, Universitätsstr. 1 40225 Düsseldorf ); Series Editor: Hugo Kubinyi (Comb. Chemistry / Mol. Model. ZHF/G, A 30, BASF AG 67056 Ludwigshafen ); Series Editor: Gerd Folkers (Dept. of Applied BioSciences, ETH Zürich Winterthurer Str. 190, CH-8057 Zürich ); Editor: Oliver Zerbe ( ) |
| The vast progress made in the investigation of biomolecules using NMR has only recently been rewarded with the Nobel Prize for Kurt Wüthrich. Edited by a former coworker of Wüthrich, this book presents the theoretical background on NMR of biomolecules, plus the use of NMR techniques in determining the structures of proteins and nucleic acids. BioNMR spectroscopy offers a universal tool for examining the binding of an active substance to its target protein. Its use thereby benefits the rational development of drugs. This interaction can now be investigated in a hitherto unparalleled precision and displayed in 3D - an important prerequisite for the targeted development of new active substances. The latest methods for characterizing substance-receptor complexes are demonstrated backed by many case studies from pharmaceutical research. Thus it comes as no surprise that a large number of the authors are working for leading pharmaceutical companies. With its successful mixture of basic information and application strategies, coupled with many real-life examples, this is an invaluable guide for both NMR spectroscopists and pharmaceutical researchers.
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| Cloth Bound |
450 Pages
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Item #:
Price: |
3527304657
$120.00 |
John Wiley & Sons, Inc. | |
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